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In a phase 2 clinical study, patients who were administered 20 mg/day lorcaserin attained an average weight loss of 3.6 kg, which was significantly greater than the average weight loss of 0.3 kg in the placebo group [82]

Furthermore, it is able to induce apoptosis independently of cross-linking [58]

Safety: Its important to note that while AOD-9604 demonstrated excellent safety and tolerability, the clinical development program was ultimately discontinued because efficacy for weight loss did not meet regulatory approval standards

Anti-CD38 SdAbs-based RLT In the field of sdAbs, the sdAb#2F8 was selected by our group as a promising theranostic agent for the monitoring and treatment of MM [108]
