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Phytother Res 39(9):42304246 Loya-Hernndez LP, Arzate-Quintana C, Castillo-Gonzlez AR, Camarillo-Cisneros J, Romo-Senz CI, Favila-Prez MA, Quionez-Flores CM (2025) Propolis-functionalized biomaterials for wound healing: a systematic review with emphasis on polysaccharide-based platforms

doi: 10.1002/14651858.CD006895.pub2 177

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Despite an increase in GS expression and activity, the rate of release exceeds that of synthesis, resulting in intracellular glutamine pool depletion.[11] If skeletal muscle is the major glutamine exporter, the high flow of blood through the pulmonary circulation and the presence of GS make the lungs a site for glutamine metabolism.[12] The GS gene expression is induced during sepsis.[13] Lymphocytes and macrophages are also great glutamine consumers, while in an inflammatory state, glutamine utilization is 10-fold greater in proliferating lymphocytes than in resting cells.[14] In the bowel, decreased glutamine utilization during sepsis occurs in the mucosal cells rather than in lymphatic tissue,[15] and reduced intestinal uptake of circulating glutamine has been observed during interleukin-1 (IL-1) treatment.[16] The maintenance of blood acidbase balance is essential for survival

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Potential Causes of B12 Deficiency Lets talk a little bit about what the potential causes of B12 deficiency are, because it is, as I mentioned, at least in my patient population, the most common cause of neuropathy