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Special Precautions & Warnings: For Pregnancy and breast-feeding: Pregnant and lactating mothers should not take any single supplement in higher-than-normal doses unless recommended by a health-care provider for a special condition

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Long-term data from a 52-week clinical study found that escitalopram reduced relapse risk by 2.8 times compared with placebo, with 22% of escitalopram-treated patients relapsing versus 50% on placebo, supporting maintenance treatment after improvement, according to this 52-week social anxiety relapse-prevention study on PubMed
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Prolapsed hemorrhoids tend to be quite painful when sitting and can hurt during bowel movements

Xue XC, Wu YJ, Gao MT, et al