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Description
Emodine is majorly glucuronidated by UGT1A1, 1A9, 1A10 and 2B7 (Wu et al., 2014)

and Its Bioactive Constituents: Update and Review

Collectively, these findings indicate that disruption of the glucagon receptor not only modifies the gene expression profile of cells but also alters the pancreatic islet microenvironment

Its not a drawback so much as a critical characteristic that must be understood and accounted for

The 4.8mcg here is at 200% DV, well above the 2.4mcg RDA

Travis Laver 3 , VMD, PhD, ACVVIM
