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Oncogenesis (2014) 3(11):e128

Free radicals and oxidative stress Oxidative stress is a result of an increase in the generation of free radicals or a decrease in the number of antioxidants

Sun X, Ou Z, Xie M, Kang R, Fan Y, Niu X et al

Control Release 353 , 650662 (2023)

While often temporary, this increase in platelets carries serious risks: Deep vein thrombosis (blood clots in deep veins, usually in legs) Pulmonary embolism (blood clots in lungs) Arterial thrombosis (clots in arteries) Cerebrovascular events (strokes) Coronary artery thrombosis (heart attacks) Splanchnic vein thrombosis (clots in abdominal veins) The risk is particularly high in: Elderly patients Those with pre-existing heart disease Patients with inherited blood-clotting disorders Immobilized individuals Those with hardened arteries Neurological Symptoms and Joint Pain Paradoxically, B12 replacement can temporarily worsen or trigger new neurological symptoms

This also includes the gastric mucosa, where oral supplementation with PC has been shown to provide gastrointestinal support to damaged cells