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Once synthesized, it is distributed through the bloodstream and becomes highly concentrated in tissues that demand massive amounts of continuous energy, specifically the skeletal muscles and the myocardium (heart muscle), which contain over 95% of the body's total carnitine stores

There are currently three drug therapies approved by the United States (US)s Federal Drug Administration (FDA): pregabalin, duloxetine, and milnacipran

D-carnitine supplementation has been found to induce liver inflammation, oxidative stress, and apoptosis in animal studies (13)