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Changes in the concentrations of amino acids in the cerebrospinal fluid that correlate with pain in patients with fibromyalgia: implications for nitric oxide pathways

Blocking c-MET to Overcome Resistance to Anti-vascular Endothelial Growth Factor Treatment To overcome the c-MET protein overexpression that occurs with the neutralization of VEGF by BVZ, the addition of a c-MET inhibitor would be helpful

This is the period where premature dose escalation most commonly occurred