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doi: 10.1186/s12889-017-4968-2

Several potential therapeutic targets related to cholesterol ester metabolism have been identified, including: Acyl-CoA:Cholesterol Acyltransferase (ACAT) : Inhibitors of ACAT, such as avasimibe and pactimibe, reduce cholesterol ester synthesis and intracellular lipid accumulation, offering potential benefits for reducing atherosclerosis progression and improving lipid profiles

J lipid Res (1999) 40(9):167785

Five studies could not be included in the quantitative synthesis because they did not report depressive-symptom outcomes with the summary statistics needed to calculate the effect size