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Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 resolution

Technological Primer Recent studies indicate that beside water and salt homeostasis and digestion and absorption of nutrients, another key function of the intestine is to regulate the trafficking of environmental antigens across the host mucosal barrier (1)

Lanet, J.L

Furthermore, this study uncovers a previously unrecognized function of the START domain: by binding membranes, it promotes homotypic interactions between LE/Lys, thereby regulating their positioning

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(This might relate to propofols inhibition of NMDA receptors, which blocks tolerance and withdrawal.) Propofol suppresses respiration, which can be helpful among ventilated patients to reduce ventilator dyssynchrony