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As a result, the skin becomes tighter and more resilient, reducing sagging and the appearance of fine lines

Pre-clinical studies done on C57BL/6J mice using total body irradiation (9 Gy) found that radiation reduced -diversity of gut microbiota, while urolithin A (UroA), a gut microbial metabolite, helps in alleviating radiation-induced apoptosis in intestinal cells by suppressing P53 signaling pathway (Zhang et al., 2021c

Despite the limitations of multi-organ interactions, cell experiments are available for investigating cell-specific mechanistic pathways

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Breastfeeding: The guidance is similarwhile evidence of harm is limited, most healthcare providers recommend avoiding retinoids during breastfeeding as a precautionary measure