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The field requires urgent Phase I/II human trials before any clinical recommendations can be made

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Interestingly, we observed that the cecal microbiome of previously-obese animals returned to the lean state through NNMTi treatment and LD switch was distinct from the cecal microbiome of continuously lean control animals

If signs of vitamin B12 toxicity are observed, its essential to seek immediate medical attention at the nearest healthcare facility for prompt treatment

Adding vasoconstrictors can make anesthesia last longer by reducing blood flow

Vitamin B12 can affect the absorption of other medications