glutathione conjugation as a bioactivation reaction Glutathione-Mediated of Anticancer Drugs: An Overview of Mechanisms and Biological Significance for Drug Detoxification and Scheme 1. Two pathways for

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GSH in erythrocytes is an indicator of intracellular GSH status, the overall health of cells and of the ability to endure toxic challenges

GSH depletion and concomitant increase in O&NS and mitochondrial dysfunctions play a role in the pathophysiology of diverse neuroimmune disorders, including depression, myalgic encephalomyelitis/chronic fatigue syndrome and Parkinsons disease, suggesting that depleted GSH is an integral part of these diseases

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