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10.3389/fimmu.2022.1003376 Front

Although Se incorporation is challenging, Se is essential for life and required for the proper enzymatic function of selenoproteins such as glutathione peroxidases (GPX) and thioredoxin reductases (TrxR) [34]

It is crucial to use the exact same culture medium (including any vehicle controls) to prepare the standard curve for the ELISA

3 HO-1: from heme degradation to ferroptosis modulation HO-1, encoded by HMOX1 , is a heme-metabolizing enzyme predominantly expressed in the spleen and reticuloendothelial system ( Heme, an iron-rich porphyrin compound, is widely distributed across various cell types and represents the most significant source of iron ions aside from ferritin ( Figure 1 )

showed that zearalenone can cause irreversible damage to the skeletal structure of germ cells (loss of mitochondria and golgi) and also has a certain impact on DNA replication and transcription, causing DNA damage (57)

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