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Guehring T, Urban JP, Cui Z, Tirlapur UK: Noninvasive 3D vital imaging and characterization of notochordal cells of the intervertebral disc by femtosecond near-infrared two-photon laser scanning microscopy and spatial-volume rendering
Why did dihexa never enter clinical trials if the animal data was promising? Pharmaceutical companies evaluate preclinical compounds based on risk-benefit calculus, intellectual property landscape, competitive market positioning, and probability of regulatory approval many promising animal compounds are abandoned before human trials because the investment required for Phase 13 studies (often $50$100 million) cannot be justified
10.3109/03008207.2014.884083 51 D'IppolitoG.DiabiraS.HowardG
Integrating single-cell and spatial transcriptomics to elucidate intercellular tissue dynamics
Risk of ischemic heart disease in women after radiotherapy for breast cancer
