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Studies on human aortic endothelial cells (Table 3) showed that CBD reduced phosphorylation of c-Jun N-terminal kinase (JNK), nuclear factor B (NF-B), ribosomal protein S6 kinase (p70S6K) and signal transducer and activator of transcription 5 (STAT5), and increased phosphorylation of cAMP response element - binding protein (CREB), extracellular signal - regulated kinase 1/2 ( ERK1/2), protein kinase B (Akt) and endothelial nitric oxide synthase (NOS)

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