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Advisory Committee Meeting | Mixed Event Title July 23-24, 2026: Meeting of the Pharmacy Compounding Advisory Committee July 23 - 24, 2026 Date: July 23 - 24, 2026 Time: 8:00 a.m

Pro-inflammatory actions of red blood cell-derived DAMPs

(A) Activity of wild type (WT) and C300S M pro (1 M enzyme) following a 30-minute pre-incubation of 1.2 M M pro with 10 mM oxidized glutathione

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BPC-157 Supports Vascular and Neurological Repair One underappreciated hallmark of long COVID is endothelial dysfunction damage to the lining of blood vessels that impairs circulation, oxygenation, and tissue delivery.7 BPC-157 has demonstrated angiogenic (new blood vessel formation) effects in research models, upregulating VEGFR2 and promoting collateral circulation in ischemic tissue.8 This matters for two reasons: Cardiovascular symptoms (breathlessness, reduced exercise tolerance, tachycardia) may partly reflect impaired tissue oxygenation from vascular damage Neurological symptoms (brain fog, cognitive impairment) may similarly reflect reduced cerebral blood flow BPC-157's neuroprotective effects shown across models of traumatic brain injury, dopamine dysregulation, and serotonin syndrome also suggest value in supporting the neurotransmitter disruption many long COVID patients experience.9 BPC-157 Modulates Inflammation Without Immune Suppression This is critical