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72 The overexpression of components of cysteine catabolic pathways in cancer cells is likely to result in increased pyruvate production

Prognostic Significance of Tumor Immune Microenvironment and Immunotherapy: Novel Insights and Future Perspectives in Gastric Cancer

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10.1007/s13311-018-0656-x 24 BelarbiK.CuvelierE.DesteeA.GressierB.Chartier-HarlinM

This idea dates back to seminal work from Eagle, who showed that supplementation with extracellular GSH supports cell growth in cystine-free conditions 22

The research is clear: patients with nonalcoholic fatty liver disease who received glutathione supplementation showed significant improvements in liver enzyme markers (ALT levels decreased from 68.9 36.1 IU/L to 58.1 33.5 IU/L) and reduced liver fat accumulation