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A large number of studies have assessed peripheral biomarkers of oxidative stress such as antioxidant levels

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The importance of oxidized protein folding-Nrf2-ER calcium axis regulation mechanisms has also been found in cell culture models of familial amyotrophic lateral sclerosis (ALS) with superoxide dismutase (SOD1)-muted (Tokuda et al., 2019)

The Institutional Review Board of each participant hospital belongs to same country (South Korea)
Nerve Health and Function: B12 maintains the myelin sheath that protects nerves and ensures proper signalling within the nervous system
