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Diabetes Res Clin Pract 157:107843

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Grundke-Iqbal et al., 1986

Starting with modified furan leads to direct dual-functionalisation of oligonucleotides Showing the broad applicability of this methodology by functionalising eight different primary amine-bearing oligomers (phosphodiester-, phosphorothioate- or peptidic backbone, LNA modifications, internal amines and different terminal amines), we next evaluated the single-site one-step dual-functionalisation of AONs

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The results revealed an inverse association between the concentrations of total carotenoids, -carotene, -carotene, and lutein in blood and breast cancer risk