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Cell Death Dis (2021) 12(9):834
doi: 10.1186/s13046-019-1027-0 208 KangDHKimYLeeJHKangHSChungC
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TuppenHAFehmiJCzerminBGoffriniPMeloniFFerreroIet al
In response, the brain activates the microglia which undergo morphological changes, that is, polarization to the M2 phenotype, and begin producing various inflammatory mediators, including TNF- , IL-1, and IL-6
