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Other GLP-1R, GIPR, and glucagon receptor (GCGR) poly-agonists are in development and have been tested in phase 1 and phase 2 clinical trials, including GLP-1R/GCGR agonists, GLP-1R/GLP-2R agonists, and triple GLP-1R/GIPR/GCGR agonists (abstracts presented at the American Diabetes Association Annual Meeting in June, 2022 and (7))

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Further, a study comparing bariatric surgery and GLP-1 receptor agonists found that both interventions similarly reduced the risk of developing obesity-related cancers (242)Wolff Sagy Y, et al