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elegans survival 16,17,18 (Supplementary Tables 1 and 2) and selectively induced the HSR, as shown by the marked induction of HSP genes such as hsp-70 and hsp-16.2 , and only modestly induced the mitochondrial stress gene hsp-6 and the oxidative stress gene gst-4 , whereas other oxidative or endoplasmic reticulum stress-response markers were not induced (Supplementary Fig

Interestingly, in addition to LXR activation, LXR repression also affects tumor progression
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Subjects with cancer, cardiovascular disease, gastrointestinal disease, liver, and renal diseases were excluded from the study

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