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Description
Sirtuins, particularly SIRT1, need NAD+ as a cofactor for protein deacetylation
They are usually induced by corticosteroids, anti-tubercular drugs, anticonvulsivants, antipsychotics and some anti-cancer agents [1]
Stopping injections will lead to recurrence of deficiency, as the underlying malabsorption cannot be corrected
Epigenetics and Metabolism at the Crossroads of Stress-Induced Plasticity, Stemness and Therapeutic Resistance in Cancer
It also affects appetite
But Australian experts say that while promising, the trials shortcomings mean theres not enough evidence to warrant prescribing it
