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The proposed mechanism involves potentiation of existing opioid tone rather than direct opioid receptor agonism, which may explain the absence of classical tolerance and dependence patterns
Scanlon, K., Travers, R., Coleman, T., Bauer, G
2 AbbottN
The code does not vary by the dose of tirzepatide administered, whether the patient receives 2.5mg or 15mg, the administration code remains the same
doi: 10.1053/j.gastro.2008.10.055
