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Nan KS, Karuppanan K, Kumar S
Additionally, treatment with an agonist of the peroxisome proliferator activated receptor gamma (PPAR), pioglitazone, increased the expression of EAAT2 in human glioblastoma cells and reduced their viability, indirectly confirming the inverse correlation between the level of this transporter and cell survival [82]

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The rationale: insulin is a potent anti-lipolytic signal
Metabolic imbalance associated with methylation dysregulation and oxidative damage in children with autism

Biomaterials 35 , 74707478 (2014)
