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Palomar Rios A, Molina Botella I

Mitophagy in maintaining skeletal muscle mitochondrial proteostasis and metabolic health with ageing

The only randomised, double-blind clinical trial evaluating recombinant human BDNF in diabetic polyneuropathy failed to demonstrate significant improvements in conventional nerve conduction or sensory endpoints, although post hoc analyses suggested potential benefits in selected small-fibre domains, highlighting the importance of patient selection and outcome measures in future studies [62]

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Ruminant Meat and Milk Contain -valerobetaine, Another Precursor of Trimethylamine N-Oxide (TMAO) like -butyrobetaine