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Discovery of a potent, selective, and orally bioavailable c-met inhibitor: 1-(2-Hydroxy-2-methylpropyl)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide (AMG 458)

Although this review also advocates for the exploration of personalized medicine approaches, the aforementioned limitations prevent comprehensive details on the effective implementation of these strategies

Reactivation of herpesvirus has interestingly been hypothesised as a key mechanism in the development of ME/CFS (128)

doi: 10.1007/s12035-015-9364-2

& Weaver, T