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There are several reasons why you might consider this treatment

Cardiovascular side effects, while less common, may include changes in heart rate, with some patients experiencing a mild increase in resting heart rate of two to three beats per minute on average

Taking Vitamin B12 injections or performing any other injections requires the use of new needles

The removal of a drug from the body through metabolism (usually in the liver) and excretion (usually through kidneys)

In severe cases, this may be accompanied by sweating, shortness of breath, chest pain, hoarseness, facial swelling, and fever

For those in the semaglutide group, the weight-loss trajectory continued to week 65 and then was sustained for the study period through week 208 (10.2% for the semaglutide group, 1.5% for the placebo group