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As in biological systems, metallic cations act as exogenous sources of OS by stimulating ROS formation in ART culture media, and metal chelators such as EDTA and transferrin can ameliorate the production of ROS [43]

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Finally, the combination of novel drug therapies, a better understanding of the -synuclein clearance by astrocytes, the use of neurotoxic models, growth factors use and other therapies that increase astrocyte survival and its antioxidant function may shed light on a prospective cure of PD in the near future

doi: 10.1016/s0278-5846(00)00181-0

Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia

Increased motor cortex white matter volume predicts motor impairment in autism