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In addition, the culture conditions of human primary hepatocytes are relatively harsh, they can only be cultured in the short term and cannot be subcultured indefinitely, which is not conducive to the progress of the experiment

doi: 10.1161/01.cir.0000055318.09997.1f

RAR, Retinoic acid receptor

10.1016/j.addr.2021.113955 274 PeiS.SunW.HanQ.WangH.LiangQ

In addition to this, treatment of A549 and H3122 cells with SAG caused an increase in intracellular Fe 2+ concentration, ROS levels and MDA content as well as a decrease in GSH content, which was thus shown to also trigger ferroptosis in lung cancer [217]

[DOI] [PMC free article] [PubMed] [Google Scholar] 137.Liu Y., He X.-Q., Huang X., Ding L., Xu L., Shen Y.-T., Zhang F., Zhu M.-B., Xu B.-H., Qi Z.-Q., et al
