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However, preclinical data on animals (gerbils) showed that both U-101033E and U-104067F can significantly attenuate the post-ischemic loss of dopaminergic nigrostriatal neurons (Miyaji et al., 2015

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Low-grade adverse events (hepatitis, thyroiditis, and oral mucositis) occurred after the first cycle of ipilimumab/nivolumab, but did not require immunotherapy discontinuation

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