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doi: 10.1038/nn.4325 288 SaherG.StumpfS

Romanyuk ND, Rigden DJ, Vatamaniuk OK, Lang A, Cahoon RE, Jez JM, et al

Acta , 1362 , 11-23, Nandi, S

90 , 122 DEufemia 155 suggested that low brain tryptophan availability due to a low serum Try/LNAA (large natural amino acids) ratio may be one of the mechanisms involved in altering serotonergic function in autism, as well as lower total plasma tryptophan and Try/LNAA ratio in people with signs of behavioral disturbances and depression

It has only been within the past decade or so that an increasing number of patients have been diagnosed with these disorders, leading some clinicians to question their prevalence