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If the treatment is inadequate due to poor understanding of B12 metabolism, and symptoms return as a result, that's due to poor research/lack of adequate knowledge on how to treat B12 deficiency properly in PA

For example, in the presence of IL-12 and IFN-, T helper cells can differentiate into Th1 cells which play an important role in the host defense against intracellular pathogens [72]

Nature 593 , 244248 (2021)
Diabetes Care

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Primary antibodies like COL1 (#72026, Cell Signaling Technology), VEGFA (ab52917, Abcam), CD31 (ab182981, Abcam), p-PI3K (TA3242, Abmart), p-eNOS (PC3447, Abmart) and corresponding fluorescent secondary antibodies (ab150079 and ab150077, Abcam) were used
