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The dysregulation of ROS and GSH balance can tip the scales toward an oxidatively stressed microenvironment, contributing to the transformation and survival of cancerous cells

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With the promotion of researches, some methods are found to overcome the liver toxicity of DB

Fan K, Xu J, Jiang K et al (2019) Determination of multiple mycotoxins in paired plasma and urine samples to assess human exposure in Nanjing, China

Glutathione ( 3a ) also reacts with organic electrophiles ( R ), such as several reactive metabolites of environmental contaminants and pharmaceutical drugs, and with metal ions of thiophilic elements ( M ) to yield the corresponding glutathione thioethers ( 5a ), alkyl-cysteines ( 5b ) and mercapturic acids ( 5c )

The application of nanocarriers can effectively encapsulate or adsorb ferroptosis modulators, thereby improving their solubility and delivery efficiency
