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Moraes found that ADSC-derived EVs may activate the Janus kinase (JAK)/signal transducer and activator of transcription (STAT-3) pathway through epidermal growth factor receptor 1 (EGFR-1)/IL-6, thereby promoting breast cancer cell migration and metastasis (Moraes et al

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[DOI] [PubMed] [Google Scholar] 53

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Moreover, case 3 (ILBC metastatic to the ovary) featured regions with pure conventional ILBC growth pattern and other regions with almost pure tubular elements