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All the authors approved its final version, and agreed to be accountable for all aspects of the work

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These extracellular vesicles exerted anti-inflammatory effects on colonic epithelial cells by suppressing the NF-B signaling pathway, ultimately reducing TNF- and IL-6 expression and restoring intestinal barrier integrity

However, considering the dual functionality of AARS1 in protein translation and lactylation, targeted inhibition strategies should be employed judiciously

The degassed solution was saturated with 18 O 2 for 2 h and heated at 70C

Pure Encapsulations Acetyl-l-carnitine consists of acetyl-l-carnitine HCl, a synthetically derived amino acid