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Similar neuroprotective effects have been observed in mouse models of rotenone-induced PD as well, through the inhibition of -synuclein phosphorylation and aggregation, protection of mitochondrial function, inhibition of neuroinflammation, modulation of autophagy, attenuation of oxidative stress and restoration of ER balance (Wang D

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Of note, presenting the portal and caval hypertension and organ congestion, it is reasonable that in the isoprenaline control rats, the azygos vein appears to be collapsed, and the superior mesenteric vein and inferior caval vein are apparently congested (Figure 1 and Figure 2)

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