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(d) Cognitive behavior was assessed by time spent in familiar or novel arm of the y-maze
Just to get a sense how complex this process is, here is roughly how CPI is calculated

(Rev.123, 8-19-16)

n is an integer selected from 0-4

Insulin and IGF-1 improve mitochondrial function in a PI-3K/Akt-dependent manner and reduce mitochondrial generation of reactive oxygen species in Huntingtons disease knock-in striatal cells

The clinical trials that showed disappointing results used oral administration
