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While ATOR treatment decreased the viability, migration, and proliferation of glioma cells, it did not show a synergistic effect with TMZ, since the individual effect of these drugs is similar to the combined treatment [223]

[DOI] [PubMed] [Google Scholar] 237.Aitken R.J

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Additionally, silymarin increases vitagenes that improve cellular resilience, such as sirtuins, thioredoxin (Trx), and heat shock proteins (HSPs) (Trovato Salinaro et al., 2014

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This article covers the specific mechanisms that make the stack viable, the dose protocols researchers are exploring, and the monitoring parameters that distinguish safe co-administration from reckless polypharmacy