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While it is found in foods such as red meat, dairy products, avocados, and some fish, dietary intake is often not sufficient to meet higher metabolic demands, especially for athletes or individuals following vegetarian or vegan diets

Metabolic obesity: the paradox between visceral and subcutaneous fat

Britt, E.B

J Biol Chem 294(50):1942419435

Carnitine has been reported as highly efficient in the downregulation of pro-inflammatory cytokines TNF- and IL-6 in murine models of cancer cachexia [24, 36], liver fibrosis [23] and in blocking TNF--induced insulin resistance in skeletal muscle cells [48]

However, compared with the intensive mechanistic studies of carnitine in mammals, the majority of the studies of carnitine in fish have only focused on the effects of carnitine on the fishs growth and body composition, whereas studies on the systemic regulation of nutritional metabolism by carnitine in fish, and the underlying mechanisms, are lacking