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These cells exhibit high expression of genes associated with ECM synthesis and organization, such as ACAN and COL2A1 (Gan et al., 2021)

Serum B12 levels alone may not be adequate to identify a deficiency in B12

CD8 + T cells with tissue-resident memory (TRM) signature have been recently highlighted in the contribution to tissue fibrosis in aged mice (93)

14 (S7), 304S-309S309S

A controlled blood volume removal was conducted until the death or stabilized low blood pressure (30-35 mm Hg)

These are products of metabolism (metabolites) that provide insight into: Digestive and microbiome health (ex: malabsorption, SIBO) Cellular energy production and mitochondrial health Neurotransmitter levels Vitamins that are cofactors to certain enzymes, including B vitamins Toxins and detoxification capacity Amino acids the building blocks of protein Essential amino acids (the ones we need from the diet) Nonessential amino acids (the ones that the body makes from the others) Intermediate metabolites of amino acid metabolism that inform us about B vitamin status, the nitrogen cycle and methylation