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This peptide is among the best-studied ones in the cytoprotection area, having extensive pre-clinical history since the early 1990s with experiments conducted using the models of injuries in different organs in various animals

After that initial period, it is common to continue injections monthly, though less frequent intervals might be OK if cobalamin blood levels are supportive

P21 is a small tetra-peptide derived from the most active region of CNTF (ciliary neurotrophic factor), the amino acid residues 148-151

Uses: FDA-approved for major depression in adults

Others maintain full doses of each

In these cases, taking vitamin B12 orally, sublingually (under the tongue), or by infusion may help improve fatigue