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The theoretical expectationminimal systemic absorption of a 7,649 Da protein through intact skinsuggests low risk of systemic effects
doi: 10.1016/j.jhep.2014.05.033
Nrf2, nuclear factor erythroid 2 like 2
The present model was also compared to the human LTC4S structure (PDB ID: 2UUH) in Supplementary Fig
Furthermore, the human body relies on ingested sulfur amino acids, such as L-Methionine, for the synthesis of protein, as well as for biologically active sulfur
Other enzymes involved in elafibranors metabolism include CYP2J2 and multiple UGTs (UGT1A3, UGT1A4, and UGT2B7)
