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An additional, 11 non-herniated human discs were used to examine causality: half of each specimen was cultured in a manner that allowed free unconstrained swelling (similar to a herniated disc in vivo), while the other half was cultured within a perspex ring that allowed constrained swelling

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Without controlled head-to-head data, any claim of a direct winner remains speculative

Step 8: Dispose and Log the Injection Dispose of the used syringe immediately in a sharps container

The canonical pyroptosis pathway is initiated by the activation of the NLRP3 inflammasome complex, which includes NLRP3, the adaptor protein ASC containing the CARD domain, and pro-caspase-1 [65]

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