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Malabsorption of vitamin B12, resulting from structural or functional damage to the stomach, where intrinsic factor is secreted or to the ileum, where intrinsic factor facilitates vitamin B12 absorption

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Humid heat exposure further increases wakefulness, decreases REM and SWS, and excessively suppresses the decrease in Tcore, whereas Tsk and whole body sweat loss are not affected [43]

Through metagenomic sequencing and in vitro coculture experiments of peripheral blood mononuclear cells (PBMCs), it was verified that butyrate can selectively expand peripheral blood Tregs in RA patients, inhibit the activation of conventional T cells (Tconvs), downregulate the production of anti-citrullinated peptide antibodies (ACPA), and reduce cartilage and bone tissue damage

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Stimulation of collagen and glycosaminoglycan synthesis The best-documented effect