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Cyclosporin A was administered in a few cases with tacrolimus neurotoxicity

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doi: 10.19672/j.cnki.1003-6504.2019.12.004

However, researchers have also developed hypotheses about its other potential mechanisms of action, such as potential anti-inflammatory and possible immunomodulatory impact

Although proper iron metabolism is required for the physiological process in oligodendrocytes, aberrant iron homeostasis under pathological situations may exacerbate oxidative stress in oligodendrocyte linage cells and lead to cell damage [59, 62]

4) Lab/serology strategy Broad infectious workup (AFB multiple, fungal serologies), HIV and basic immune screen