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Mice fed HFD had higher blood glucose, triglyceridemia, cholesterolemia, and higher serum IL-1 associated with impaired learning and memory

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Targeting glutamine transporters and downstream enzymes involved in glutamine metabolism holds significant promise in enhancing anti-tumor immunity

This study reveals structural insights into p53 binding to FOXO4/FOXO4-DRI, informing the development of p53-targeted senolytics for age related diseases.