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Both PANS and PANDAS are clinical diagnoses differentiated by the abrupt onset of symptoms as listed below

doi: 10.1016/j.apsb.2021.02.012 [DOI] [PMC free article] [PubMed] [Google Scholar] 93.Singh Y, Meher JG, Raval K, et al

Several clustered genes identified by the WGCNA analysis are under the control of Nrf2

The purpose of this study is to measure change in glycemic control and prandial insulin independency over 52 weeks with teplizumab Investigator Michael J Haller Status Accepting Candidates Ages 1 Year - 25 Years Sexes All GNTI-122-T1D-1001 This is a 78-week single arm, multi-center, Phase 1 study to evaluate the safety, tolerability, cellular kinetics, and biomarker changes in C-peptide over time of GNTI-122, an investigational cell therapy manufactured from a participant's own blood Investigator Brittany S Bruggeman Status Accepting Candidates Ages 18 Years - 55 Years Sexes All TN-36 This Phase 2 study is a 2-arm, multi-center, double-masked (masking of the participant, care provider and investigator), placebo-controlled, 2:1 randomized trial design in new onset T1D participants (within 100 days of diagnosis)