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Hepatology 2012;56:73546 [DOI] [PubMed] [Google Scholar] 52.Du YC, Lai L, Zhang H, Zhong FR, Cheng HL, Qian BL, Tan P, Xia XM, Fu WG.Kaempferol from penthorum chinense pursh suppresses HMGB1/TLR4/NF-kappaB signaling and NLRP3 inflammasome activation in acetaminophen-induced hepatotoxicity

7 A Clinical Perspective Despite limited case reports and studies and our general caveats with regard to research confounds with antioxidants, NAC appears to be promising in a number of psychiatric syndromesparticularly those associated with oxidative stress (e.g., schizophrenia and bipolar disorder) and impulsive/compulsive symptoms (e.g., trichotillomania, pathological nail biting, gambling, and substance misuse)

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