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2003 Feb;24(2):307-11

The complex travels through the small intestine until it reaches the terminal ileum, where specialised receptors called cubam (a complex of cubilin and amnionless proteins) recognise and facilitate the uptake of the B12-IF complex into enterocytes (intestinal cells)

In practical terms, patients are usually interested in it for: For patients who cannot tolerate strong retinoids, acids, or aggressive routines, GHK-Cu may be considered as part of a gentler plan

The IF-vitamin B12 complex passes via receptor-mediated endocytosis in the terminal ileum while avoiding proteolysis and acting as a carrier for the vitamin

Meng L, Guo X, Yang X, et al

This is why sterile technique isn't just for surgeryit's paramount in peptide research
